BioCore™ – Modular Bioprocess Management System

BioCore™ is a modular, high-performance, licensable bioprocess management platform designed for monitoring, control, and automation across a wide range of bioprocessing systems. Its modular architecture enables seamless integration of virtually any peripheral, providing the flexibility to support diverse processes — from laboratory-scale bioreactors to pilot plants and large-scale, thousand-liter photobioreactors (PBRs).

Supported Fermentation & Bioprocess Types

BioCore™ supports the most common fermentation and cultivation strategies used across research, pilot, and industrial bioprocessing environments, including:

• Batch Fermentation
  Closed-system operation with defined start and end points.
• Fed-Batch Fermentation
  Controlled substrate feeding to optimize growth and product yield.
• Continuous Fermentation
  Steady-state operation with continuous input and output streams.
• Perfusion Cultivation
  Continuous media exchange while retaining biomass in the reactor.
• Chemostat Operation
  Growth rate controlled by a limiting nutrient under steady-state conditions.
• Phototrophic Cultivation
  Light-driven processes used in photobioreactors (PBRs), including algae and cyanobacteria.
• Heterotrophic Cultivation
  Carbon-source-driven microbial growth typical in industrial fermentation.
• Mixed-Mode Cultivation
  Hybrid processes combining phototrophic and heterotrophic phases.

Seamless Hardware Integration

BioCore™ communicates with a wide range of devices using multiple industrial and embedded protocols:

• Serial / RS-485 / Modbus
  • Hamilton dissolved oxygen (DO) sensors
  • Hamilton pH (pH) sensors
  • Hamilton optical cell density sensors
  • Bronkhorst mass flow controllers
• GPIO / PWM / I2C
  • Custom peristaltic pumps for pH and media control
  • Atlas Scientific temperature sensors
  • Status LEDs for system and process indication
  • Physical buttons and digital inputs for local control
  • Stirring motors with adjustable RPM
• Display Interfaces
  • HDMI output for local operator displays and HMIs

Technology Stack

• Linux-based Operating System
  Designed to run natively on Linux for stability, security, and long-term maintainability.
• Multi-Architecture Support
  Supported CPU architectures include amd64, arm64, arm, and riscv64, enabling deployment from embedded devices to industrial servers.
• Modern Graphical User Interface
  KDE Plasma–style UI delivering a clean, responsive user experience for local operation.
• Modular Package Deployment
  APT-based package management for safe, incremental updates and feature modularity.
• JavaScript Runtime (Embedded V8 Engine)
  High-performance, event-driven control logic with maximum flexibility and rapid development.
• D-Bus Integration
  Native D-Bus communication for inter-process coordination, service control, and system-level integration.
• Service Management & Reliability
  Full systemd integration ensuring robust startup, supervision, and lifecycle management.